Fig. 13

An example for an impact as “Literature-inconsistent hypotheses”. A knowledge graph with pairwise relationship limitation type “More than two entities interacting together” is constructed from PMID 33933117. Knowledge inference is performed on a node participants for Alzheimer’s disease drug trials and any of three nodes (plasma A\(\beta\)42/40 ratio, ApoE proteotype, and age). All of these three hypotheses may be inaccurate because the discovery statement is about combining three biomarkers as a blood-based diagnostic test