Fig. 3

An example of using pairwise relationships and nested relationships for a complex entity. Mutation: Familial Alzheimer’s disease mutations, Gene: amyloid protein precursor, Process: proteolysis. Upper: A statement in PMID 33450230 with a highlighted complex entity. Bottom left (a): Represent a complex entity with pairwise relationships. The statement is represented with independent pieces of information: A mutation in a gene and a gene altering a process. Bottom right (b): Represent a complex entity with nested relationships. The statement is represented with dependent pieces of information. A process of a mutation in a gene alters another process