Fig. 6

An example for a pairwise relationship limitation type “Experimental model as a constraint”. Left (a): Only one neurodegenerative disorder tau pathology instead of a finding antibody semorinemab reduces tau pathology is linked to an experimental model a transgenic mouse model. Only one biomarker tau instead of a finding antibody semorinemab engages tau is linked to an experimental model patients with Alzheimer’s disease. Right (b): Each of two findings in a graph (antibody semorinemab::reduce::tau pathology and antibody semorinemab::engage::tau) is grouped as an entity. Each grouped entity is connected to a corresponding experimental model with a relation of in