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Table 3 Summary of pairwise relationship limitation types and frequency of occurrence in 56 articles. Alternative representation structures that can overcome the limitation are assigned for each limitation type. One article may have more than one limitation type

From: Enriched knowledge representation in biological fields: a case study of literature-based discovery in Alzheimer’s disease

Paiwise relationship limitation type

#of abstracts

Alternative representation

Mechanism/process from a modified entity

22

Nested relationship

Modifier that adds granular information for entities

17

Nested relationship

Experimental model as a constraint

16

Nested relationship

Use of a method

12

Nested relationship

Specific context as a constraint

10

Nested relationship

Lack of context for a general concept

5

Hypergraph

More than two entities interacting together

2

Hypergraph