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Table 4 Impacts on knowledge inference with different pairwise relationship limitation types and aspects of impacts (EF: Experiment Feasibility, ES: Experiment Success, EG: Experiment Granularity)

From: Enriched knowledge representation in biological fields: a case study of literature-based discovery in Alzheimer’s disease

Impacts on knowledge inference

Pairwise relationship limitation type(s)

EF

ES

EG

Experimentally infeasible hypotheses

Lack of context for a general concept

Literature-inconsistent hypotheses

More than two entities interacting together Experimental model as a constraint Use of a method Specific context as a constraint Mechanism/process from a modified entity

Oversimplified hypotheses explanations

Modifier that adds granular information for entities